Rajan Singh, Ph.D.
Assistant Professor, Department of Internal Medicine and Division of Endocrinology
Charles R. Drew University of Medicine and Science
1731 E. 120th Street
Los Angeles, CA 90059
Phone: (323) 563- 9328
Email: rasingh@cdrewu.edu or rajansingh@mednet.ucla.edu
Dr.
Singh received his M.S. degree in Biochemistry from Calcutta
University, India. He was awarded his PhD. Degree in Molecular Biology
from Jadavpur University, India. Dr. Singh joined UCLA School of
Medicine for his post doctoral research. He currently holds dual
faculty appointment as an Assistant Professor at Charles R. Drew
University and the UCLA School of Medicine.
Research Interests I
am interested in understanding the signal transduction pathways that
regulate cell proliferation, apoptosis and differentiation. Currently I
am investigating the role of androgens during cell differentiation
using pluripotent stem cells as model system.
Selected Publications
- Rajan
Singh, Jorge N. Artaza, Wane E. Taylor, Melissa Braga, Xin Yuan, Nestor
F. Gonzalez-Cadavid, and Shalendar Bhasin. Testosterone inhibits
adipogenic differentiation in 3T3-L1 cells: nuclear translocation of
androgen receptor complex with ß-catenin and TCF4 may bypass canonical
Wnt signaling to downregulate adipogenic transcription factors. (In
press, Endocrinology, 2005).
- Singh R,
Artaza JN, TaylorWE, Gonzalez-Cadavid NF , Bhasin S. (2003) Androgens
stimulate myogenic differentiation and inhibit adipogenesis in C3H
10T1/2 pluripotent cells through an androgen receptor-mediated pathway.
Endocrinology, 144 (11):5081-5088.
- Rajan
Singh, Shehla Pervin and Gautam Chaudhuri. Caspase -8 mediated BID
Cleavage and Release of Cytochrome c during N-Hydroxy-L- Arginine
induced Apoptosis in MDA-MB-468 Cells: Antagonizing Effects of
L-Ornithine. Journal of Biological Chemistry (2002); (277):
37630-37636.
- Rajan Singh, Shehla P
