Jorge N. Artaza, M.Sc. Ph.D.
Assistant Professor, Career Academic, Department of Internal Medicine, Endocrinology Division.
Research Assistant Professor Department of Biological Sciences.
Charles R. Drew University of Medicine and Science
1731 E. 120th Street
Los Angeles, CA 90059
Phone: (323) 563-4915
Email: joartaza@cdrewu.edu
Dr.
Artaza received his M.S. degree in Biochemistry from the University of
Buenos Aires, Argentina. He was awarded his Ph.D. Degree in Cellular
and Molecular Biology from the same university. He was supervisor at
the Clinical Biochemistry Training Laboratory, lecturer in Hematology
and staff clinical biochemist at the School of Biochemistry, University
of Buenos Aires. He was a Fellow at the Methodist Center for
Reproduction and Transplantation Immunology of Methodist Hospital of
Indiana and visiting scientist at the Tissue Typing Laboratory,
University of California, Los Angeles (UCLA).
Research Interests
Current
research interests focus on the role of Myostatin and androgens in the
maintenance of skeletal muscle mass and on myogenic differentiation.
Selected Publications
- “Endogenous
Expression and localization of Myostatin and its relation to MHC
distribution in C2C12 skeletal muscle cells. Jorge N. Artaza, Shalender
Bhasin, Con Mallidis, Wayne Taylor, Kun Ma, Nestor Gonzalez-Cadavid.
Journal of Cellular Physiology (JCP), 2002, Feb; 190(2): 170-179.
- “Androgens
Stimulate Myogenic Differentiatin and Inhibit Adipogenesis in C3H
10T1/2 pluripotent cells Through an Androgen Receptor-Mediated
Pathway”. Rajan Singh*, Jorge N. Artaza*, Wayne Taylor*, Nestor
Gonzalez-Cadavid, Shalender Bhasin. *Equal contribution. Endocrinology,
2003 Nov; 144 (11): 5081-8.
- ”Delta-4-androstene-3,17-dione
(4-androstenedione) Binds Androgen Receptor, Promotes Myogenesis in
Vitro, and Increases Serum Testosterone Levels, Fat-Free Mass, and
Muscle Strength in Hypogonadal Men”. Ravi Jasuja, Panduraman Ramaraj,
Ricky Phong Mac, Atam B. Singh, Thomas W. Storer, Jorge Artaza, Aria
Miller, Rajan Singh, Wayne E. Taylor, Martin I. Lee, Tina Davidson,
Indrani Sinha-Hikim, Nestor Gonzalez-Cadavid and Shalender Bhasin. J.
Clin. End. & Metab 2004 Nov; 10.1210/jc.2004-1577.
- Tetrahydrogestrinone
is an Androgenic Steroid that Stimulates Androgen-Receptor Mediated
Myogenic Diferentiation in C3H10T (1/2) Multipotent Mesenchymal cells
and Promotes Muscle Accretion in Orchidectomized, Male Rats”. R.
Jasuja, D.H. Catlin, A. Miller, YC. Chang, KL Herbst, B. Starcevic, J.
N. Artaza, R. Singh, G. Datta, A. Sarkissian, C. Subarathnam M. Baker
and S. Bhasin, Endocrinology published June 23, 2005 as
doi:10.1210/en.2005-0448.
- Myostatin
Inhibits Myogenesis and Promotes Adipogenesis in 10T(1/2) Mesenchymal
Multi-potent cells". J. N. Artaza, S. Bhasin, T. R. Magee, S.
Reisz-Porszasz, R. Shen, N. P. Groome, M.M. Fareez and N F
Gonzalez-Cadavid. Endocrinology,2005 Aug, 146 (8): 3547-57
Awards
Distinguished
Research Award in Basic Science, at Charles R. Drew University of
Medicine and Science. Division of Endocrinology Metabolism and
Molecular Medicine. 2001-2002 Academic year.
Travel Grant
Award in conjunction with ENDO 2003 in Philadelphia sponsored by The
Endocrine Society and participating of the ENDO 2003 Research Summaries
Book (RSB).
Excellence in Endocrinology Research Award in
Basic Science, at Charles R. Drew University of Medicine and Science.
Division of Endocrinology Metabolism and Molecular Medicine. July 2003.
Glaxo Smith-Kline Endocrinology Scholar Award at the American Federation for Medical Research (AFMR). January 2004.
Glenn
Foundation Endocrinology and Aging Travel Grant Award in conjunction
with ENDO 2004 in New Orleans. This award is given to only three people
per year and is sponsored by the Paul F. Glenn Sponsorship Fund in
cooperation with the American Federation for Aging Research. June 2004.
