Department of Neuroscience mission is expressed in the research conducted by its faculty and students with an emphasis on the health issues most profoundly affecting the minority and economically disadvantaged citizens of our country. Our faculty realize that with new knowledge comes a keen sense of the potential and appreciation of how far we still need to progress to ensure that the mortality and morbidity of curable disease among our disadvantaged populations are within the range of society as a whole.

The Department is nationally and internationally recognized in epilepsy, stroke, and brain injury research. The following is a selective sample of some of the study projects conducted by our faculty:

1. UCLA Head injury research center program/national institutes of health (NIH). 1994-1999
2. Long- Term Open label study of Topimax Topiramate. Protocol YOL, Phase III. 1992-1995
3. Cambridge Neuroscience, Inc. Efficacy and Safety of CERESTAT (Aptiganel HCL) as a neuroprotective following severe traumatic brain injury. 1996-1998
4. The Clomethiazole Acute stroke study in ischemic stroke (Class-I): A double blind, parallel group, multinational, multicenter study of the efficacy and safety of I.V. Clomethiazole compared to placebo in patients with acute ischemic stroke. 1997
5. The Clomethiazole Acute stroke study in Acute Intracerebral Hemorrhage (Class –H): A double blind, parallel group, multinational, multicenter study of safety of I.V Clomethiazole compared to placebo in patients with acute intracerebral hemorrhage. 1997
6. The Clomethiazole Acute stroke study in t-PA treated ischemic stroke (Class- T): A double blind, parallel group, multinational, multicenter study of safety of I.V Clomethiazole compared to placebo in patients treated with t-PA (tissue plasminogen activator) for acute ischemic stroke. 1997
7. Losigamone as monotherapy in the treatment of complex partial seizures. 1997-1999
8. Vitamin Intervention for Stroke Prevention (VISP). 1999-2003
9. African-American Antiplatelet Stroke Prevention Study (AAASPS). 2000-2003
10. Siblings With Ischemic Stroke Study (SWISS). 2001-Present
11. Management of Atherothrombosis with Clopidogrel in High-Risk patients with recent Transient Ischemic Attack or Ischemic Stroke (MATCH). 2001-2004
12. Efficacy and Safety Evaluation of a Single Intravenous Dose of Dexanabinol in patients Suffering from Severe Traumatic Brain Injury. 2003-2004
13. Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA). 2003-2005
14. Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS). 2003-Present
15. Phase II, randomized, Pharmacokinetic, Dose finding, and dose frequency determination using rt-PA in intraventricular hemorrhage. 2003-Present
16. Novo Nordisk F7CBI-1587: A Multi Center Observational study to evaluate the incidence and magnitude of hemorrhage progression of cerebral contusions and the identification of important safety Issues following traumatic brain injury. 2004-2005.